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Forward-Looking Statements: This article reflects information reviewed in July 2026

Although vascular endothelial growth factor (VEGF) is critical for developmental and pathological angiogenesis, recent evidence showed that autocrine VEGF could also contribute to the maintenance of vascular homeostasis (4)

Besides, the cost deters it from making its way into low- and middle-income countries, where people are not only most affected by obesity, but are also at risk of cardiovascular death, where it makes up nearly 80% of the global burden, according to the National Institutes of Health